{"id":8389,"date":"2021-11-15T15:08:46","date_gmt":"2021-11-15T20:08:46","guid":{"rendered":"https:\/\/www.cnl.ca\/?page_id=8389"},"modified":"2024-01-30T21:01:18","modified_gmt":"2024-01-31T02:01:18","slug":"canadian-nuclear-research-initiative-health-cnri-h","status":"publish","type":"page","link":"https:\/\/www.cnl.ca\/health-science-2\/canadian-nuclear-research-initiative-health-cnri-h\/","title":{"rendered":"Canadian Nuclear Research Initiative: Health (CNRI-H)"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;grid&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; z_index=&#8221;&#8221; css=&#8221;.vc_custom_1606934660265{margin-top: 64px !important;margin-bottom: 64px !important;}&#8221;][vc_column width=&#8221;1\/2&#8243;][vc_column_text]Canadian Nuclear Laboratories\u2019 (CNL) Canadian Nuclear Research Initiative-Health Program (CNRI-H) is a program developed by CNL to further the realization of its mission of contributing to the health of Canadians. Through CNRI-H, CNL provides financial support<sup>1<\/sup> along with its expertise, experience, capabilities and makes this available and accessible to the healthcare community to advance new life saving radiopharmaceutical solutions. CNRI-H is a turnkey solution that integrates both funding and project execution in one award.<\/p>\n<p>The focus of the program is Radiopharmaceutical Therapy optimization, Toxicology and Pre-clinical Evaluation research. The goal of the program is to accelerate the optimization of therapeutic isotopes production and\u00a0 the\u00a0 clinical translation of targeted radiopharmaceuticals for the benefit of Canadians whilst increasing the safety and efficacy of therapies that involve radiopharmaceuticals.[\/vc_column_text][vc_empty_space][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_column_text]CNL will be working with the selected third-party proponents in Canada and internationally on projects to be delivered as contract research. CNL would be financially supporting these projects by contributing significantly to the project cost as a matching grant in-kind (cost sharing details are elaborated in section 2.1).<\/p>\n<p>Annually, CNL will issue CNRI-H call for proposals (CFP), review the proposals received and select the proposals that fall within defined preselection criteria. CNL will then proceed to formalize agreements with the selected party (ies) to deliver the project(s). CNL does not intend to share in the ownership of R&amp;D deliverables under the CNRI-H program. Project execution will begin in May 2024 and may continue for a maximum of 24 months.<\/p>\n<p>For more information, or to submit your proposal, email\u00a0<a href=\"mailto:commercial@cnl.ca\">commercial@cnl.ca<\/a>.[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;grid&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; z_index=&#8221;&#8221; background_color=&#8221;#e5e5e5&#8243; css=&#8221;.vc_custom_1605205158572{margin-top: 64px !important;}&#8221;][vc_column][vc_empty_space height=&#8221;64&#8243;][vc_column_text]<\/p>\n<h2>CNRI Program Timeline<\/h2>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;grid&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; z_index=&#8221;&#8221; background_color=&#8221;#e5e5e5&#8243;][vc_column width=&#8221;1\/2&#8243;][vc_column_text]<strong><em>January 29, 2024<\/em>\u00a0\/<\/strong> CNRI-H call for proposals open<\/p>\n<p><strong><em>March 11, 2024<\/em>\u00a0\/<\/strong> Deadline for proposal submission. 12 PM ET[\/vc_column_text][vc_empty_space][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_column_text]<strong><em>March 25, 2024<\/em>\u00a0\/<\/strong> CNL reviews and selects proposals to proceed to negotiations.<\/p>\n<p><strong><em>May 31, 2024<\/em>\u00a0\/<\/strong> Successful agreements announced and work begins.[\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;grid&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; z_index=&#8221;&#8221;][vc_column][vc_empty_space height=&#8221;64px&#8221;][vc_column_text]<\/p>\n<h2 id=\"Focus_Areas\" class=\"h3\">Focus Areas<\/h2>\n<div class=\"panel\">\n<p>A call for proposals (CFP) will be issued as part of the CNRI program. Included in each CFP will be a list of focus areas. The list of focus areas is as follows:<\/p>\n<\/div>\n<p>[\/vc_column_text][vc_empty_space height=&#8221;64px&#8221;]<div class=\"qode-accordion-holder clearfix  qode-toggle qode-initial \">\n\t\r\n<h3 class=\"clearfix qode-title-holder\" id=\"btn-radiochemistry-for-rpt\" aria-controls=\"radiochemistry-for-rpt\" aria-expanded=\"false\" tabindex=\"0\">\r\n<span class=\"qode-tab-title\">\r\n\t    <span class=\"qode-tab-title-inner\">\r\n        Radiochemistry for RPT    <\/span>\r\n<\/span>\r\n<span class=\"qode-accordion-mark\">\r\n    <span class=\"qode-accordion-mark-icon\">\r\n        <span class=\"icon_plus\"><\/span>\r\n        <span class=\"icon_minus-06\"><\/span>\r\n    <\/span>\r\n<\/span>\r\n<\/h3>\r\n\r\n<div id=\"radiochemistry-for-rpt\" class=\"qode-accordion-content \"  aria-hidden=\"true\" aria-labelledby=\"btn-radiochemistry-for-rpt\">\r\n    <div class=\"qode-accordion-content-inner\">\r\n        [vc_column_text]<\/p>\n<ul>\n<li>Optimization of radioisotope production to increase RP quality<\/li>\n<li>Proof-of-concept for new delivery systems for targeted radiopharmaceuticals<\/li>\n<li>Validation of delivery systems for targeted therapies<\/li>\n<\/ul>\n<p>[\/vc_column_text]    <\/div>\r\n<\/div>\r\n<h3 class=\"clearfix qode-title-holder\" id=\"btn-improving-rpt-toxicology\" aria-controls=\"improving-rpt-toxicology\" aria-expanded=\"false\" tabindex=\"0\">\r\n<span class=\"qode-tab-title\">\r\n\t    <span class=\"qode-tab-title-inner\">\r\n        Improving RPT Toxicology    <\/span>\r\n<\/span>\r\n<span class=\"qode-accordion-mark\">\r\n    <span class=\"qode-accordion-mark-icon\">\r\n        <span class=\"icon_plus\"><\/span>\r\n        <span class=\"icon_minus-06\"><\/span>\r\n    <\/span>\r\n<\/span>\r\n<\/h3>\r\n\r\n<div id=\"improving-rpt-toxicology\" class=\"qode-accordion-content \"  aria-hidden=\"true\" aria-labelledby=\"btn-improving-rpt-toxicology\">\r\n    <div class=\"qode-accordion-content-inner\">\r\n        [vc_column_text]<\/p>\n<ul>\n<li>Optimization and validation of new RP therapy efficacy In vitro and In vivo<\/li>\n<li>Optimization of radiopharmaceutical based therapy, focused on combined therapies toxicity in vivo<\/li>\n<\/ul>\n<p>[\/vc_column_text]    <\/div>\r\n<\/div>\r\n<h3 class=\"clearfix qode-title-holder\" id=\"btn-accelerating-clinical-translation\" aria-controls=\"accelerating-clinical-translation\" aria-expanded=\"false\" tabindex=\"0\">\r\n<span class=\"qode-tab-title\">\r\n\t    <span class=\"qode-tab-title-inner\">\r\n        Accelerating clinical translation    <\/span>\r\n<\/span>\r\n<span class=\"qode-accordion-mark\">\r\n    <span class=\"qode-accordion-mark-icon\">\r\n        <span class=\"icon_plus\"><\/span>\r\n        <span class=\"icon_minus-06\"><\/span>\r\n    <\/span>\r\n<\/span>\r\n<\/h3>\r\n\r\n<div id=\"accelerating-clinical-translation\" class=\"qode-accordion-content \"  aria-hidden=\"true\" aria-labelledby=\"btn-accelerating-clinical-translation\">\r\n    <div class=\"qode-accordion-content-inner\">\r\n        [vc_column_text]<\/p>\n<ul>\n<li>Optimization and validation of radiopharmaceutical based therapy for new targets \/ new applications<\/li>\n<li>Pre-clinical evaluation targeted therapies<\/li>\n<\/ul>\n<p>[\/vc_column_text]    <\/div>\r\n<\/div><\/div>[vc_empty_space][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;grid&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;left&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; css=&#8221;.vc_custom_1622394980916{margin-top: 150px !important;padding-top: 70px !important;padding-bottom: 70px !important;background-color: #0077d9 !important;}&#8221; z_index=&#8221;&#8221;][vc_column][vc_row_inner row_type=&#8221;row&#8221; type=&#8221;full_width&#8221; text_align=&#8221;left&#8221; css_animation=&#8221;&#8221; css=&#8221;.vc_custom_1591098772816{padding-top: 25px !important;}&#8221;][vc_column_inner]<div class='q_icon_with_title tiny normal_icon left_from_title '><div class=\"icon_text_holder\" style=\"\"><div class=\"icon_text_inner\" style=\"\"><div class=\"icon_title_holder\"><div class=\"icon_holder \" style=\" \"><span data-icon-type=\"normal\"   style=\"\" class=\"qode_iwt_icon_holder q_font_awsome_icon fa-lg  \"><i class=\"qode_icon_font_awesome fa fa-dashcube qode_iwt_icon_element\" style=\"color: #ffffff;\" ><\/i><\/span><\/div><h2 class=\"icon_title h6\" style=\"color: #ffffff;font-weight: 400;\">Potential Award Details<\/h2><\/div><p style='color: #ffffff'>Annually, CNL will enter into a series of jointly funded R&amp;D projects that will utilize S&amp;T (Science and Technology) services from CNL to accelerate the discovery, development and approval of targeted radiopharmaceuticals for the benefit of Canadians. Projects must be within the CNRI program focus areas. Applicants are expected to, at a minimum, match the value contributed by CNL in monetary or in-kind contribution.<\/p><\/div><\/div><\/div>[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;grid&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;center&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; css=&#8221;.vc_custom_1622395104533{padding-top: 82px !important;padding-bottom: 70px !important;}&#8221; z_index=&#8221;&#8221;][vc_column][vc_column_text css=&#8221;.vc_custom_1622414899626{padding-bottom: 70px !important;}&#8221;]<\/p>\n<h2 class=\"h3\">Related Documents<\/h2>\n<p>[\/vc_column_text][vc_row_inner row_type=&#8221;row&#8221; type=&#8221;full_width&#8221; text_align=&#8221;left&#8221; css_animation=&#8221;&#8221;][vc_column_inner]<div class='featured-reports  '><div class=\"report-item hide_img\"><a itemprop=\"url\" href=\"https:\/\/www.cnl.ca\/wp-content\/uploads\/CNRI-Health-Program-Guidelines-2024-2025.pdf\" title=\"CNRI-H: Program Guidelines\" target=\"_blank\"><span class=\"report-content\"><h3  class=\"report_title small\">CNRI-H: Program Guidelines<\/h3><span class=\"report_pdf_link\">Read report <\/strong><\/span><\/span><\/a><\/div><div class=\"report-item hide_img\"><a itemprop=\"url\" href=\"https:\/\/www.cnl.ca\/wp-content\/uploads\/2021\/11\/CNRI-Health-Terms-and-Conditions-2022-2023.pdf\" title=\"CNRI-H: Terms &#038; Conditions\" target=\"_blank\"><span class=\"report-content\"><h3  class=\"report_title small\">CNRI-H: Terms &#038; Conditions<\/h3><span class=\"report_pdf_link\">Read report <\/strong><\/span><\/span><\/a><\/div><\/div>[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row css_animation=&#8221;&#8221; row_type=&#8221;row&#8221; use_row_as_full_screen_section=&#8221;no&#8221; type=&#8221;grid&#8221; angled_section=&#8221;no&#8221; text_align=&#8221;center&#8221; background_image_as_pattern=&#8221;without_pattern&#8221; css=&#8221;.vc_custom_1622395129586{padding-top: 90px !important;padding-bottom: 120px !important;background-color: #f5f5f5 !important;}&#8221; z_index=&#8221;&#8221;][vc_column][vc_single_image image=&#8221;97&#8243; img_size=&#8221;full&#8221; alignment=&#8221;center&#8221; qode_css_animation=&#8221;&#8221;][vc_column_text css=&#8221;.vc_custom_1622414916972{padding-top: 30px !important;padding-bottom: 43px !important;}&#8221;]<\/p>\n<h2 class=\"h3\">Get in touch with us to learn more:<\/h2>\n<p>[\/vc_column_text][vc_column_text]<div class=\"frm_forms  with_frm_style frm_center_submit frm_style_formidable-style\" id=\"frm_form_1_container\" >\n<form enctype=\"multipart\/form-data\" method=\"post\" class=\"frm-show-form  frm_pro_form \" id=\"form_contact-form\" >\n<div class=\"frm_form_fields \">\n<fieldset>\n<legend class=\"frm_screen_reader\">Send us your Feedback<\/legend>\r\n\r\n<div 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css=&#8221;.vc_custom_1606934660265{margin-top: 64px !important;margin-bottom: 64px !important;}&#8221;][vc_column width=&#8221;1\/2&#8243;][vc_column_text]Canadian Nuclear Laboratories\u2019 (CNL) Canadian Nuclear&#8230;<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":1460,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"episode_type":"","audio_file":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","filesize_raw":"","footnotes":""},"class_list":["post-8389","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Canadian Nuclear Research Initiative: Health (CNRI-H) - Canadian Nuclear 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